Mouse Model – DLBCL/FL
Gain access to our mouse models in FL/DLBCL, including vavP-BCL2 strain, KMT2D-flox CD19-cre strain and BTG1-KO strain (and more). These models enable to investigate novel drug targets and test for drug efficacy and toxicity
Mouse Model – Natural killer/T-Cell lymphoma
Gain access to this mouse model (p53-KO x JARID-KO-flox x CD4-cre) for investigating NK/T-cell lymphoma biology, identifying novel drug targets and testing for drug efficacy and toxicity
Mouse Model – Peripheral T-cell lymphoma (PTCL)
Gain access to this mouse model to investigate PTCL biology, identifying novel drug targets and testing for drug efficacy and toxicity
CAR-NK cells generation and characterization
Our expert teams specialize in the precise engineering of CAR-NK cells, tailoring them to recognize specific tumor antigens with high precision. Through functional characterization, we validate the potency and specificity of these engineered cells, ensuring their efficacy in targeting cancer cells while sparing healthy tissues.
Acute lymphoblastic leukemia cell lines
Explore our available ALL cell lines to investigate ALL biology, identify novel drug targets, and test drug toxicity and efficacy.
T-cell lymphoma cell lines
Explore our available T-cell lymphoma cell lines (>21). Conduct in-depth experiments to unravel the biology of T-cell lymphoma and identify novel drug targets.
CITE-seq
CITE-seq combines single-cell RNA sequencing with protein detection to analyze cell populations in detail. Our platform facilitates comprehensive characterization of cell types, states, and interactions, enabling to profile immune cell responses,to identify rare cell populations, or to unravel disease mechanisms
scBCR-seq & scTCR-seq
scBCR-seq and scTCR-seq profiles B or T cell receptors at the single-cell level, revealing their diversity, specificity, and clonal dynamics. These techniques provides insights into adaptive immunity, vaccine responses, antigen recognition and antibody-based therapies.
Genetically engineered mouse models
Gain access to our expertise to engineer unique « à la carte » transgenic mouse models.
Mouse Model – B-cell Lymphoma
Gain access to our engineered mouse models, including CD19-Cre transgenic strain (allowing conditional engineering in B cells), BCL2tracer strain (mimicking sporadic t(14;18) translocation), AID-Cre-ERT2 KI/KO strain (used to monitor memory B cell population), RosaYFP Reporter strain, MLL4 f/F strain, Cas9-GFP Cre strain, and BCL2/KDMT2D knock-out strain (either as a syngenic chimera model or xenograft), and […]