Mouse Model – Eµ-myc
We provide Eµ-myc mouse model for non-Hodgkin B cell lymphoma study, characterized for response to chemotherapies and to metabolic inhibitors, metabolomic (carbon tracing), and transcriptomic.
In vitro modelisation – Naïve B cells to plasma cell differentiation
We offer an in vitro model of B-cell terminal differentiation, based on the isolation and activation of donor-derived B-cells. This system allows functional studies of specific proteins through gene expression modulation with antisense technology and is fully characterized by immunoglobulin isoform analysis.
Long term in vitro culture of chronic lymphocytic leukemia primary cells
We provide a primary cell culture platform derived from patient samples, enabling precise gene expression modulation and comprehensive drug testing. This system supports target discovery and the evaluation of small molecules, antibodies, and CAR-T cell therapies.
Mouse Model for lymphoid neoplasms – DLBCL
Explore our mouse models designed respectively for the study of DLBCL, Burkitt Lymphoma, Amyloid light-chain amylosis, Multiple Myeloma, or Fanconi Syndrom, Light and heavy chain deposition disease. These models enable the identification of novel therapeutic targets as well as the evaluation of drug efficacy and toxicity.
Transgenic mouse model development
Gain access to our expertise to engineer unique « à la carte » transgenic mouse models.
ScienceLeadR
ScienceLeadR is an experts’ centric platform dedicated to connect the ecosystem of Life Sciences : Experts, Organizations, Academic Societies, BioTech, MedTech, Pharma Industry, … We provide a unique solution to qualify experts and organizations on all expertise at local or worldwide level. ScienceLeadR qualified more than 3.7 million experts. Based on a proprietary medical ontology, […]