Multicellulare Agregates of Lymphoma Cells (MALC)
Explore complex tumor biology with our Multicellular Aggregates of Lymphoma Cells (MALC) model. It mimics the 3D structure and microenvironment of lymphoma, providing a robust system for studying cell-cell interactions, tumor progression, and therapeutic responses. The MALC model enables more physiologically relevant insights compared to traditional 2D cultures, supporting the development of targeted lymphoma therapies.
3D Co-Culture of Lymphoma Cells with Gamma Delta T Cells
Explore our 3D co-culture system combining lymphoma cell lines and gamma delta T cells from healthy donors. This advanced model recreates the tumor microenvironment, allowing detailed study of immune-tumor interactions, gamma delta T cell cytotoxicity, and potential therapeutic mechanisms.
Patient-Derived Lymphoma Spheroids (PDLS)
Explore our Patient-Derived Lymphoma Spheroids (PDLS), a cutting-edge 3D organoid model developed directly from patient samples. PDLS offer an accurate representation of tumor architecture and microenvironment, enabling the study of tumor behavior, drug response, and personalized treatment strategies.
Immunohistochemistry
We offer precise staining and analysis of tissue samples, enabling the detection and localization of specific proteins within their histological context. Our IHC platform provides critical insights into disease mechanisms, biomarker expression, and therapeutic target validation.
Multiplexed Immuno-Fluorescence
We enable simultaneous detection of multiple targets within a single tissue section, providing a detailed spatial understanding of cellular environments. Our mIF services are ideal for studying co-localization, cellular heterogeneity, and biomarker discovery.
Spatial Transcriptomics and Proteomics
By capturing the spatial distribution of RNA and proteins in situ, our transcriptomic and proteomic platforms provides a comprehensive view of gene and protein expression respectively, within their native tissue context. Based on multiple approaches (from single-cell spatial-Omics to imaging mass spectrometry) and our lymphoid neoplasm expertise, we explore spatially defined expression patterns, cell-cell interactions, […]
Transgenesis platform
Our transgenesis platform enables the generation of customized mouse models through precise genetic modifications, including gene overexpression, knock-in mutations, and conditional gene targeting. These models provide powerful tools to study gene function, disease mechanisms, and therapeutic strategies.
HemSys
HemSys is a Multidisciplinary Consultation Meeting (MCM) software package designed for use by healthcare professionals in the field of haematology. Each partner centre can use the tool securely to manage patients treated in its establishment. The HemSys tool consists of a Multidisciplinary Consultation Meeting (MCM) software package for haematology and an associated secure database.
Advanced Flow Cytometry
Our platform combines multiparameter and spectral flow cytometry with FACS to analyze and isolate diverse cell populations, enabling high-resolution study of cellular heterogeneity and function in biomedical research.
French Connect
French Connect is an innovative liquid biopsy platform for sensitive ctDNA-based MRD monitoring in lymphoid malignancies. It enables early relapse prediction (PET-scan correlated), MRD follow-up in clinical trials, and ancillary studies. Developed by multi-disciplinary experts from 10 leading French academic centers, this platform offers ready-to-use panels for DLBCL, PMBL, and FL, along with an optimized […]