Patient-Derived Lymphoma Spheroids (PDLS)
Explore our Patient-Derived Lymphoma Spheroids (PDLS), a cutting-edge 3D organoid model developed directly from patient samples. PDLS offer an accurate representation of tumor architecture and microenvironment, enabling the study of tumor behavior, drug response, and personalized treatment strategies.
Immunohistochemistry
We offer precise staining and analysis of tissue samples, enabling the detection and localization of specific proteins within their histological context. Our IHC platform provides critical insights into disease mechanisms, biomarker expression, and therapeutic target validation.
Multiplexed Immuno-Fluorescence
We enable simultaneous detection of multiple targets within a single tissue section, providing a detailed spatial understanding of cellular environments. Our mIF services are ideal for studying co-localization, cellular heterogeneity, and biomarker discovery.
Lymphoma Data Hub (LDH)
The LDH is a collaborative research platform in digital health, specialized in data management and technological support for biomedical research. Our services include secure cloud hosting for health data, end-to-end data management from raw data deposit to ready-to-use datasets, and the deployment of advanced tools to enable research projects in artificial intelligence and bioinformatics.
CeVi Collection
The CeVi collection is a unique collection of cryopreserved viable human cells from lymphomas and reactive lymphoid tissues. It is structured around a national network of Biological Resource Centres (BRCs) and is dedicated to the use of CALYM consortium members and their partners, with the aim of accelerating lymphoma research.
Advanced Co-Culture Systems with Immune Components
We specialize in co-culturing primary cells or cell lines with patient-derived macrophages, NK cells, CD8+ T cells, and PBMCs to study immune synapse formation and cellular dynamics. Our system enables precise modeling of immune responses, providing critical data for immunotherapy development and disease mechanism research.
Ex vivo Expansion of Patient-Derived iNKT Cells
Enhance your immunotherapy research with our specialized platform for the ex vivo expansion of invariant natural killer T (iNKT) cells from patient samples. Our optimized protocols ensure robust expansion of iNKT cells, providing a reliable source of these critical immune effectors for research and therapeutic applications.
Ex vivo Expansion of Normal and Pathological CD34+ Cells
Explore our advanced in vitro model for the expansion of normal and pathological CD34+ cells. Optimized protocols enable efficient and scalable production of hematopoietic stem and progenitor cells, providing a robust system to study blood disorders, stem cell biology, and regenerative therapies in both basic and preclinical research.
Mapping the Epigenetic Landscape: ChIP-seq, CUT&Run, and CUT&Tag
Our epigenetics methodologies, including Chromatin Immunoprecipitation (ChIP-seq), CUT&Run and CUT&Tag, provide new insights into the regulatory mechanisms governing gene expression and chromatin structure. It allows researchers to dissect complex regulatory networks, identify novel transcriptional regulatory elements, and uncover the molecular basis of diseases.
Mouse Patient Derived Xenographt (Mouse-PDX) – Lymphoma
Explore our Mouse PDX models to investigate lymphoma biology, identify novel drug targets, or test for drug efficacy and toxicity. PDX models available for different lymphoma subtypes: AITL, CTCL,MCL, DLBCL, MZL, and more