Advanced Co-Culture Systems with Immune Components
We specialize in co-culturing primary cells or cell lines with patient-derived macrophages, NK cells, CD8+ T cells, and PBMCs to study immune synapse formation and cellular dynamics. Our system enables precise modeling of immune responses, providing critical data for immunotherapy development and disease mechanism research.
Ex vivo Expansion of Patient-Derived iNKT Cells
Enhance your immunotherapy research with our specialized platform for the ex vivo expansion of invariant natural killer T (iNKT) cells from patient samples. Our optimized protocols ensure robust expansion of iNKT cells, providing a reliable source of these critical immune effectors for research and therapeutic applications.
Ex vivo Expansion of Normal and Pathological CD34+ Cells
Explore our advanced in vitro model for the expansion of normal and pathological CD34+ cells. Optimized protocols enable efficient and scalable production of hematopoietic stem and progenitor cells, providing a robust system to study blood disorders, stem cell biology, and regenerative therapies in both basic and preclinical research.
Patient-Derived Lymphoma Spheroids (PDLS)
Explore our Patient-Derived Lymphoma Spheroids (PDLS), a cutting-edge 3D organoid model developed directly from patient samples. PDLS offer an accurate representation of tumor architecture and microenvironment, enabling the study of tumor behavior, drug response, and personalized treatment strategies.
In Ovo Patient Derived Xenographt (AVI-PDX)
Explore our InOvo PDX models to investigate lymphoma biology, identify novel drug targets and testing for drug efficacy and toxicity.
Mouse Patient Derived Xenographt (Mouse-PDX) – Lymphoma
Explore our Mouse PDX models to investigate lymphoma biology, identify novel drug targets, or test for drug efficacy and toxicity. PDX models available for different lymphoma subtypes: AITL, CTCL,MCL, DLBCL, MZL, and more
Patient Derived Organoids – Follicular lymphoma
Discover our organoid model derived from FL patient primary cells (tumor and microenvironment), cultured in vitro on a peptide-based gel matrix. This system enables drug and target discovery through gene expression modulation and extensive screening of small molecules, antibodies, and CAR-T cells. Each sample is linked to clinical data and integrated into a predictive model […]
2D-culture of primary cells from patients
Explore our 2D primary cell culture (with or without stroma) derived from patient samples (DLBCL, FL, MCL, MM…), enabling in-depth studies on B and T cells. Uncover new opportunities for drug and target discovery through precise gene expression modulation and comprehensive drug testing, encompassing small molecules, antibodies, and CAR-T cells.
In vitro modelisation – Naïve B cells to plasma cell differentiation
We offer an in vitro model of B-cell terminal differentiation, based on the isolation and activation of donor-derived B-cells. This system allows functional studies of specific proteins through gene expression modulation with antisense technology and is fully characterized by immunoglobulin isoform analysis.
Long term in vitro culture of chronic lymphocytic leukemia primary cells
We provide a primary cell culture platform derived from patient samples, enabling precise gene expression modulation and comprehensive drug testing. This system supports target discovery and the evaluation of small molecules, antibodies, and CAR-T cell therapies.