Feline Model for Low-Grade Intestinal T-Cell Lymphoma
Explore our unique spontaneous animal model for low-grade intestinal T-cell lymphoma, a natural feline model that closely mirrors human indolent T-cell lymphoproliferative disorders of the gastrointestinal tract. This model provides novel insights into disease progression, immune response, and therapeutic interventions, offering a rare opportunity to study this condition in a natural setting.
Mouse Cell line Derived Xenographt (Mouse-CDX)
Explore our Mouse CDX models (parental and CRISPR-Cas9 engineered) to investigate lymphoma and Multiple Myeloma biology, identify novel drug targets and testing for drug efficacy and toxicity.
Genetically engineered mouse models
Gain access to our expertise to engineer unique « à la carte » transgenic mouse models.
Mouse Model – B-cell Lymphoma
Gain access to our engineered mouse models, including CD19-Cre transgenic strain (allowing conditional engineering in B cells), BCL2tracer strain (mimicking sporadic t(14;18) translocation), AID-Cre-ERT2 KI/KO strain (used to monitor memory B cell population), RosaYFP Reporter strain, MLL4 f/F strain, Cas9-GFP Cre strain, and BCL2/KDMT2D knock-out strain (either as a syngenic chimera model or xenograft), and […]
Mouse Model – DLBCL/FL
Gain access to our mouse models in FL/DLBCL, including vavP-BCL2 strain, KMT2D-flox CD19-cre strain and BTG1-KO strain (and more). These models enable to investigate novel drug targets and test for drug efficacy and toxicity
Mouse Model – Natural killer/T-Cell lymphoma
Gain access to this mouse model (p53-KO x JARID-KO-flox x CD4-cre) for investigating NK/T-cell lymphoma biology, identifying novel drug targets and testing for drug efficacy and toxicity
Mouse Model – Peripheral T-cell lymphoma (PTCL)
Gain access to this mouse model to investigate PTCL biology, identifying novel drug targets and testing for drug efficacy and toxicity
Mouse Model
Explore our available mouse models (drug resistant, immuno-competent, or immuno-deficient strains) to investigate lymphoma biology and identify novel drug targets.
Mouse Model – Eµ-myc
We provide Eµ-myc mouse model for non-Hodgkin B cell lymphoma study, characterized for response to chemotherapies and to metabolic inhibitors, metabolomic (carbon tracing), and transcriptomic.
Mouse Model for lymphoid neoplasms – DLBCL
Explore our mouse models designed respectively for the study of DLBCL, Burkitt Lymphoma, Amyloid light-chain amylosis, Multiple Myeloma, or Fanconi Syndrom, Light and heavy chain deposition disease. These models enable the identification of novel therapeutic targets as well as the evaluation of drug efficacy and toxicity.