Advanced ADCC Assays for Therapeutic Antibody Validation
Designed to rigorously evaluate the efficacy of antibodies in mediating immune cell responses against target cells, our ADCC studies provide critical data for antibody optimization and therapeutic development.
In Vivo Vaccine Response Assessment
We provide comprehensive analysis of immune responses in relevant animal models, offering detailed insights into vaccine efficacy, immunogenicity, and protective potential. Our in vivo studies are designed to validate your vaccine’s ability to generate a robust and lasting immune response, guiding your development towards successful clinical outcomes.
Regulatory T-Cell Activity Analysis
We provide detailed analysis of Treg function, including their capacity to suppress immune responses and maintain tolerance. Our studies offer key insights into Treg-mediated regulation, supporting the development of therapies targeting immune balance and autoimmunity.
CD8+ T Cell and NK Cell-Mediated Lymphotoxicity Analysis
We specialize in evaluating the ability of CD8+ T cells and NK cells to target and eliminate infected or malignant cells, providing critical insights into immune-mediated cytotoxicity. Our studies offer valuable data for the development of immunotherapies that harness the power of CD8+ T cells and NK cells.
Lymphoma Data Hub (LDH)
The LDH is a collaborative research platform in digital health, specialized in data management and technological support for biomedical research. Our services include secure cloud hosting for health data, end-to-end data management from raw data deposit to ready-to-use datasets, and the deployment of advanced tools to enable research projects in artificial intelligence and bioinformatics.
CeVi Collection
The CeVi collection is a unique collection of cryopreserved viable human cells from lymphomas and reactive lymphoid tissues. It is structured around a national network of Biological Resource Centres (BRCs) and is dedicated to the use of CALYM consortium members and their partners, with the aim of accelerating lymphoma research.
Advanced Co-Culture Systems with Immune Components
We specialize in co-culturing primary cells or cell lines with patient-derived macrophages, NK cells, CD8+ T cells, and PBMCs to study immune synapse formation and cellular dynamics. Our system enables precise modeling of immune responses, providing critical data for immunotherapy development and disease mechanism research.
Ex vivo Expansion of Patient-Derived iNKT Cells
Enhance your immunotherapy research with our specialized platform for the ex vivo expansion of invariant natural killer T (iNKT) cells from patient samples. Our optimized protocols ensure robust expansion of iNKT cells, providing a reliable source of these critical immune effectors for research and therapeutic applications.
Ex vivo Expansion of Normal and Pathological CD34+ Cells
Explore our advanced in vitro model for the expansion of normal and pathological CD34+ cells. Optimized protocols enable efficient and scalable production of hematopoietic stem and progenitor cells, providing a robust system to study blood disorders, stem cell biology, and regenerative therapies in both basic and preclinical research.
Feline Model for Low-Grade Intestinal T-Cell Lymphoma
Explore our unique spontaneous animal model for low-grade intestinal T-cell lymphoma, a natural feline model that closely mirrors human indolent T-cell lymphoproliferative disorders of the gastrointestinal tract. This model provides novel insights into disease progression, immune response, and therapeutic interventions, offering a rare opportunity to study this condition in a natural setting.