B-cell lymphoma cell lines
Explore our diverse range of B-cell lymphoma cell lines (PMBL, MCL, FL, DLBCL, BL), including parental and CRISPR- or shRNA-engineered models, and extensively characterized at molecular and phenotypic levels. Our collection also includes EBV-transformed cell lines and drug-resistant lines, supporting research on lymphoma biology, therapeutic targets, and resistance mechanisms.
Drug Testing
We offer robust evaluation of small molecules, antibodies, and CAR-T cells to accelerate therapeutic discovery and development. Utilizing state-of-the-art cell culture techniques, our platform accommodates diverse experimental needs across various models, including cell lines, primary cells sourced from patients, PDX models, and in vivo mouse models.
Exome-seq
Based on our Exome-seq technology, which sequences all protein-coding regions, we provide detailed genetic profiling of patient cell to uncover disease mechanisms and potential therapeutic targets in lymphoid neoplasms.
Mapping the Epigenetic Landscape: ChIP-seq, CUT&Run, and CUT&Tag
Our epigenetics methodologies, including Chromatin Immunoprecipitation (ChIP-seq), CUT&Run and CUT&Tag, provide new insights into the regulatory mechanisms governing gene expression and chromatin structure. It allows researchers to dissect complex regulatory networks, identify novel transcriptional regulatory elements, and uncover the molecular basis of diseases.
Mouse Cell line Derived Xenographt (Mouse-CDX)
Explore our Mouse CDX models (parental and CRISPR-Cas9 engineered) to investigate lymphoma and Multiple Myeloma biology, identify novel drug targets and testing for drug efficacy and toxicity.
Mouse Patient Derived Xenographt (Mouse-PDX) – Lymphoma
Explore our Mouse PDX models to investigate lymphoma biology, identify novel drug targets, or test for drug efficacy and toxicity. PDX models available for different lymphoma subtypes: AITL, CTCL,MCL, DLBCL, MZL, and more
Multiple Myeloma cell lines
Explore our panel of human myeloma cell lines, including parental and CRISPR- or shRNA-engineered models, extensively characterized at molecular and phenotypic levels. Our collection also includes drug-resistant lines, supporting research on multiple myeloma biology, therapeutic targets, and resistance mechanisms
Precision Gene Modulation with Antisense Oligonucleotides (ASOs)
Our advanced Antisense Oligonucleotides (ASOs) design technologys offer a versatile approach for precisely manipulating gene expression, including the potent capability of exon skipping to modulate protein production, such as Ig genes or BCR, by targeting donor splice sites. This method is compatible with both cell lines and primary cells, offering flexibility and applicability across various […]
Precision Genome Engineering: CRISPR Gene Editing, Barcoding, and Screening
Our platform enables precise genome editing in both cell lines and primary cells using CRISPR technology, supporting knockout, knock-in, gene tagging, and regulatory element modifications. Integrated with barcoding and high-throughput screening, it allows systematic functional genomics studies to dissect gene function, cellular pathways, and disease mechanisms. This combination of genome editing and scalable screening provides […]
Proteomics analysis
By employing advanced techniques for identification, quantification, and characterization, Proteomic Analysis offers a holistic understanding of protein expression patterns and functions. This powerful approach provides new insights into the molecular mechanisms underlying cellular processes, from signaling pathways to protein-protein interactions. By deciphering the proteome, we can uncover novel biomarkers, therapeutic targets, and pathways associated with […]