Advanced Co-Culture Systems with Immune Components
We specialize in co-culturing primary cells or cell lines with patient-derived macrophages, NK cells, CD8+ T cells, and PBMCs to study immune synapse formation and cellular dynamics. Our system enables precise modeling of immune responses, providing critical data for immunotherapy development and disease mechanism research.
Ex vivo Expansion of Patient-Derived iNKT Cells
Enhance your immunotherapy research with our specialized platform for the ex vivo expansion of invariant natural killer T (iNKT) cells from patient samples. Our optimized protocols ensure robust expansion of iNKT cells, providing a reliable source of these critical immune effectors for research and therapeutic applications.
Ex vivo Expansion of Normal and Pathological CD34+ Cells
Explore our advanced in vitro model for the expansion of normal and pathological CD34+ cells. Optimized protocols enable efficient and scalable production of hematopoietic stem and progenitor cells, providing a robust system to study blood disorders, stem cell biology, and regenerative therapies in both basic and preclinical research.
Feline Model for Low-Grade Intestinal T-Cell Lymphoma
Explore our unique spontaneous animal model for low-grade intestinal T-cell lymphoma, a natural feline model that closely mirrors human indolent T-cell lymphoproliferative disorders of the gastrointestinal tract. This model provides novel insights into disease progression, immune response, and therapeutic interventions, offering a rare opportunity to study this condition in a natural setting.
Multicellulare Agregates of Lymphoma Cells (MALC)
Explore complex tumor biology with our Multicellular Aggregates of Lymphoma Cells (MALC) model. It mimics the 3D structure and microenvironment of lymphoma, providing a robust system for studying cell-cell interactions, tumor progression, and therapeutic responses. The MALC model enables more physiologically relevant insights compared to traditional 2D cultures, supporting the development of targeted lymphoma therapies.
3D Co-Culture of Lymphoma Cells with Gamma Delta T Cells
Explore our 3D co-culture system combining lymphoma cell lines and gamma delta T cells from healthy donors. This advanced model recreates the tumor microenvironment, allowing detailed study of immune-tumor interactions, gamma delta T cell cytotoxicity, and potential therapeutic mechanisms.
Patient-Derived Lymphoma Spheroids (PDLS)
Explore our Patient-Derived Lymphoma Spheroids (PDLS), a cutting-edge 3D organoid model developed directly from patient samples. PDLS offer an accurate representation of tumor architecture and microenvironment, enabling the study of tumor behavior, drug response, and personalized treatment strategies.
B-cell lymphoma cell lines
Explore our diverse range of B-cell lymphoma cell lines (PMBL, MCL, FL, DLBCL, BL), including parental and CRISPR- or shRNA-engineered models, and extensively characterized at molecular and phenotypic levels. Our collection also includes EBV-transformed cell lines and drug-resistant lines, supporting research on lymphoma biology, therapeutic targets, and resistance mechanisms.
In Ovo Patient Derived Xenographt (AVI-PDX)
Explore our InOvo PDX models to investigate lymphoma biology, identify novel drug targets and testing for drug efficacy and toxicity.
Mouse Cell line Derived Xenographt (Mouse-CDX)
Explore our Mouse CDX models (parental and CRISPR-Cas9 engineered) to investigate lymphoma and Multiple Myeloma biology, identify novel drug targets and testing for drug efficacy and toxicity.