Mouse Patient Derived Xenographt (Mouse-PDX) – Lymphoma
Explore our Mouse PDX models to investigate lymphoma biology, identify novel drug targets, or test for drug efficacy and toxicity. PDX models available for different lymphoma subtypes: AITL, CTCL,MCL, DLBCL, MZL, and more
Multiple Myeloma cell lines
Explore our panel of human myeloma cell lines, including parental and CRISPR- or shRNA-engineered models, extensively characterized at molecular and phenotypic levels. Our collection also includes drug-resistant lines, supporting research on multiple myeloma biology, therapeutic targets, and resistance mechanisms
Mouse Model – DLBCL/FL
Gain access to our mouse models in FL/DLBCL, including vavP-BCL2 strain, KMT2D-flox CD19-cre strain and BTG1-KO strain (and more). These models enable to investigate novel drug targets and test for drug efficacy and toxicity
Mouse Model – Natural killer/T-Cell lymphoma
Gain access to this mouse model (p53-KO x JARID-KO-flox x CD4-cre) for investigating NK/T-cell lymphoma biology, identifying novel drug targets and testing for drug efficacy and toxicity
Mouse Model – Peripheral T-cell lymphoma (PTCL)
Gain access to this mouse model to investigate PTCL biology, identifying novel drug targets and testing for drug efficacy and toxicity
Acute lymphoblastic leukemia cell lines
Explore our available ALL cell lines to investigate ALL biology, identify novel drug targets, and test drug toxicity and efficacy.
T-cell lymphoma cell lines
Explore our available T-cell lymphoma cell lines (>21). Conduct in-depth experiments to unravel the biology of T-cell lymphoma and identify novel drug targets.
2D-culture of primary cells from patients
Explore our 2D primary cell culture (with or without stroma) derived from patient samples (DLBCL, FL, MCL, MM…), enabling in-depth studies on B and T cells. Uncover new opportunities for drug and target discovery through precise gene expression modulation and comprehensive drug testing, encompassing small molecules, antibodies, and CAR-T cells.
Genetically engineered mouse models
Gain access to our expertise to engineer unique « à la carte » transgenic mouse models.
Mouse Model – B-cell Lymphoma
Gain access to our engineered mouse models, including CD19-Cre transgenic strain (allowing conditional engineering in B cells), BCL2tracer strain (mimicking sporadic t(14;18) translocation), AID-Cre-ERT2 KI/KO strain (used to monitor memory B cell population), RosaYFP Reporter strain, MLL4 f/F strain, Cas9-GFP Cre strain, and BCL2/KDMT2D knock-out strain (either as a syngenic chimera model or xenograft), and […]