HemSys
HemSys is a Multidisciplinary Consultation Meeting (MCM) software package designed for use by healthcare professionals in the field of haematology. Each partner centre can use the tool securely to manage patients treated in its establishment. The HemSys tool consists of a Multidisciplinary Consultation Meeting (MCM) software package for haematology and an associated secure database.
ATAC-seq (bulk and single-cell)
ATAC-seq maps chromatin accessibility to reveal gene regulatory regions, both at bulk and single-cell resolution. Bulk ATAC-seq provides genome-wide snapshots of open chromatin across cell populations, while single-cell ATAC-seq uncovers cell-to-cell variability in chromatin states. This technique enables deeper understanding of gene regulation, cellular differentiation, and disease mechanisms, offering valuable insights for cancer research and […]
French Connect
French Connect is an innovative liquid biopsy platform for sensitive ctDNA-based MRD monitoring in lymphoid malignancies. It enables early relapse prediction (PET-scan correlated), MRD follow-up in clinical trials, and ancillary studies. Developed by multi-disciplinary experts from 10 leading French academic centers, this platform offers ready-to-use panels for DLBCL, PMBL, and FL, along with an optimized […]
B-cell lymphoma cell lines
Explore our diverse range of B-cell lymphoma cell lines (PMBL, MCL, FL, DLBCL, BL), including parental and CRISPR- or shRNA-engineered models, and extensively characterized at molecular and phenotypic levels. Our collection also includes EBV-transformed cell lines and drug-resistant lines, supporting research on lymphoma biology, therapeutic targets, and resistance mechanisms.
Drug Testing
We offer robust evaluation of small molecules, antibodies, and CAR-T cells to accelerate therapeutic discovery and development. Utilizing state-of-the-art cell culture techniques, our platform accommodates diverse experimental needs across various models, including cell lines, primary cells sourced from patients, PDX models, and in vivo mouse models.
Exome-seq
Based on our Exome-seq technology, which sequences all protein-coding regions, we provide detailed genetic profiling of patient cell to uncover disease mechanisms and potential therapeutic targets in lymphoid neoplasms.
In Ovo Patient Derived Xenographt (AVI-PDX)
Explore our InOvo PDX models to investigate lymphoma biology, identify novel drug targets and testing for drug efficacy and toxicity.
Mapping the Epigenetic Landscape: ChIP-seq, CUT&Run, and CUT&Tag
Our epigenetics methodologies, including Chromatin Immunoprecipitation (ChIP-seq), CUT&Run and CUT&Tag, provide new insights into the regulatory mechanisms governing gene expression and chromatin structure. It allows researchers to dissect complex regulatory networks, identify novel transcriptional regulatory elements, and uncover the molecular basis of diseases.
Mouse Cell line Derived Xenographt (Mouse-CDX)
Explore our Mouse CDX models (parental and CRISPR-Cas9 engineered) to investigate lymphoma and Multiple Myeloma biology, identify novel drug targets and testing for drug efficacy and toxicity.
CITE-seq
CITE-seq combines single-cell RNA sequencing with protein detection to analyze cell populations in detail. Our platform facilitates comprehensive characterization of cell types, states, and interactions, enabling to profile immune cell responses,to identify rare cell populations, or to unravel disease mechanisms